NC288S13

NC288S13

Both the reticular formation and BG play important roles in motor activity. The reticular formation uses integrated senxory and motor input to regulate spinal motor activity and influence muscle tone. The BG, consisting of a series of interconnected anatomic loops, is the site of reverberating circuits of electrical currents that sustain and modulate motor activity. Furthermore, the abnormalities of neurotransmitters in the BG also produce specific dyskinetic conditions, such as Parkinson disease, Huntington chorea, progressive supranuclear palsy, and Wilson disease.